Esketamine nasal spray (Spravato) is the latest and greatest treatment for depression. While effective and fast acting, this medication can also be costly. The best way to buy saxenda online.
Patients receiving ketamine are closely monitored by doctors before, during, and following their treatment at their physician’s office. Esketamine cannot be purchased over the counter but must be obtained through a certified provider.
What is ketamine nasal spray?
Esketamine nasal spray is a prescription medication prescribed to treat treatment-resistant depression. It works by counteracting certain forms of depression in the brain by increasing activity along neural pathways and reversing their effects, unlike antidepressants, which alter how the body responds to chemical triggers that lead to depression.
Ketamine, an anesthetic often used off-label to treat depression for decades, was recently approved by the FDA as a nasal spray version called Spravato – marking a significant milestone for patients suffering from severe depression who haven’t found relief through other medications.
For eligibility for Esketamine treatment, patients must have tried at least two other antidepressants without success and be diagnosed with treatment-resistant depression without psychosis or bipolar disorder in their history. The procedure may last two hours and require patients to remain under observation in a provider’s office until all potential side effects have subsided.
How is ketamine nasal spray used?
The Food and Drug Administration approved ketamine nasal spray sold under Spravato in March 2019 to treat depression that does not respond to other medications. As the first NMDA receptor antagonist to receive FDA approval as a nasal spray formulation, this groundbreaking device measures out precisely doses with every spray.
Your doctor will assess you and your symptoms to determine whether this new treatment option is a suitable treatment choice for you. In addition, they may ask about your past medical history and any medications you currently take. Before using this medicine, however, please be aware that its use could potentially increase risks of stroke, heart attack, brain injury; or blood vessel disease in your brain, chest, stomach area, arms, or legs; as well as the history of bleeding within either head or gastrointestinal tract area.
As part of your ketamine treatment, you will be monitored before, during, and for two hours following each session. A family member or friend should arrange to be available after your treatment session to drive you home after it concludes.
What should I discuss with my doctor before using esketamine nasal spray?
Your doctor must know about your medicines, including over-the-counter products and herbal or nutritional supplements. In addition, inform them if you have had blood vessel problems such as high blood pressure, heart disease, stroke, or liver disease and personal or family histories of mental/mood disorders, including psychosis.
Esketamine nasal spray should only ever be considered for treating TRD in adults who have tried two other antidepressant drugs without success or in pregnancy or breastfeeding women if one doesn’t provide relief. As such, it should never be seen as first-line therapy and shouldn’t be taken without medical supervision by anyone expecting or breastfeeding.
If you experience any of the following symptoms, seek emergency medical help immediately: chest pain, shortness of breath, sudden severe headache, changes in vision or loss of consciousness, or seizures. In addition, seek medical attention immediately if experiencing a severe allergic reaction to Esketamine, such as rashing/itching/swelling of face/tongue/throat. Esketamine medication can increase blood pressure significantly and make you dizzy when given.
How should I store esketamine nasal spray?
In the past, when people became sick, they visited their doctor to be examined and assessed by one. Then, if their pipe burst open, they called a plumber to fix it.
Esketamine (the S-enantiomer of ketamine) is a non-selective, non-competitive NMDA receptor antagonist recently approved by the FDA under Spravato for treatment-resistant depression. It may be taken alone or combined with an SSRI/SNRI medication.
TRD can cause significant morbidity for patients and costs to the healthcare service and society alike, yet many remain untreated or cannot find relief despite taking multiple antidepressants. Esketamine nasal spray represents an innovative new treatment option for TRD; unlike IV ketamine, it does not require puncturing a vein to administer, making home administration possible.
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